If you’re reading this, you’ll have heard about our newest product Future Whey, which has just been launched. It is a huge first for Bulk Nutrients and in our eyes quite possibly a world first.
While not as dramatic a moment as Neil Armstrong walking on the moon or Marty McFly travelling through time, we do think Future Whey could start a pivotal shift into changing the face of protein and supplements. This article will give you an understanding of the benefits of Future Whey, why it was developed and who could benefit from using it.
How whey protein became a bodybuilder’s best friend
For the last 10 to 20 years, whey protein isolate and whey protein concentrate have been the staples of bodybuilders. Whey protein (which is manufactured alongside the cheese making process) starts off with cow’s milk and is high in protein, low in fats and carbohydrates and once flavoured, tastes great.
Most importantly, whey protein has been proven in hundreds of studies where it has shown to build muscle and aid recovery. This is true for bodybuilders, athletes and the general population.
However, whey protein isn’t the only source of protein powder available. But it is the best-researched, and because of it’s quality amino acid profile (high levels of BCAAs and EAAs) it has always been considered one of the best sources of protein.
The rise of vegetable based proteins
In recent years, there has been an emerging trend of vegetable based proteins gathering momentum in the market. At Bulk Nutrients (where we have more than our fair share of vegan/vegetarian staff) we’ve been at the forefront of this movement with Earth Protein, and that really excites us.
Over the years we’ve been sourcing more nutritious, functional and (most importantly) better-tasting soy, pea and rice proteins. In addition to this, the vegetable based protein industry has come on in leaps and bounds through better processing methods.
Long standing Bulk Nutrients customers would have welcomed the continual development of our vegan/vegetarian-friendly protein range and we know through feedback, customers are loving our latest offerings. They’re more nutritious than ever before, completely natural and most of all, much more functional from a taste and mix-ability perspective.
Switching from whey proteins to alternatives
There are various reasons why some people have moved away from whey.
Whey is dairy based and an increasing number of people have chosen to remove dairy from their diets. This is often caused by lactose sensitivity, very occasional allergies to dairy and more commonly a preference for a more easily digestible, non-animal based product.
Whether it’s a perceived health benefit or a concern for the ethical treatment of animals, more people are looking for non-dairy proteins, and are finding awesome alternatives with products like our Earth Protein.
Player three has entered the game…
While proteins like rice, pea and soy are becoming popular, there have been some interesting developments in other areas which we have been busy exploring. We already sell Glutamine, BCAAs and EAAs as individual raw goods (you may already take these, as we’ve been selling them for ages).
While proteins like whey, soy, pea and rice are made up of a variety of amino acids, we’ve been tinkering with formulas which include all necessary BCAAs, EAAs and other conditional amino acids which match (and exceed) anything that nature can provide.
There are several challenges to doing this though. Historically free form amino acids have been very hard to flavour (you’ll know this is you’ve ever gagged on raw BCAAs) and are much more expensive than regular protein sources.
The results of this research and development has culminated in a brand new product, unlike anything the Australian market has seen before… Future Whey.
Timing is everything and it’s Future Whey time
Several factors have come together in recent times which we believe make now the perfect time for Future Whey.
Dairy pricing has continued to fluctuate, amino acids have become more functional and affordable. Most importantly, the Bulk R&D team have continued to refine their development skills, and we’ve worked collaboratively with our flavour developers in finding the best methods for formulating a delicious amino based beverage.
While many manufacturers already offer small dosed EAA type products which can be used during training, these are usually only suitable in 5 – 8g doses, which means they can’t be used as a real whey protein alternative.
Okay, so tell me about Future Whey
Bulk Nutrients’ Future Whey has had one of our longest development cycles ever – around 18 months.
It’s a completely new way to take protein, ideal at any time of the day with a unique 25 gram serve. Perhaps the biggest benefit of Future Whey is it’s huge 90% protein content, as well as the fact it contains zero fats and carbs. It also contains no lactose and is 100% dairy free.
When we began developing Future Whey, we started with a blank slate. Unlike whey and vegetable-based protein sources where the amino acid ratios are set, Future Whey’s blank slate allowed us to completely tailor the ratios based on proven research for the optimum level of muscle growth and recovery.
Most importantly, Future Whey contains 5 grams of L Glutamine per serve, in comparison to less effective Glutamic Acid which is present in whey protein. The remaining blend of Future Whey is a combination of non-essential free form amino acids, meaning Future Whey contains a total of 15 amino acids.
What does the science say about Future Whey?
Future Whey has been developed in collaboration with a biochemist after countless hours of internal and external research.
The most interesting value of the research was looking at the efficiency of whey protein when compared to a much smaller serving of essential amino acids (EAAs). Here, several studies suggested the key level of EAAs was between 10 and 12 grams. And when these smaller serves of EAAs were compared to a much higher dose of whey based protein (with similar EAA levels), the results were very similar.
From here we looked at individual non-essential amino acids and other benefits they provide, such as Glutamine in the support of immune function, as well as Glycine’s role in the synthesis of Creatine. Citrulline (in the form of Citrulline Malate) is also incorporated for its effect on vasodilation and on circulating Arginine (where it is more effective than Arginine itself!).
The key to the 25 gram dose was that we’re conscious of total daily protein requirements of individuals and that we wanted to make the product as close to a 1:1 replacement for whey as possible.
So, is Future Whey a replacement for whey?
We’ll leave that decision up to you; however, we’re extremely excited about the flexibility of Future Whey.
It has a clean, refreshing taste (with incredible launch flavours, Cola and Lemonade) which give a welcome change to milky whey based flavours. This makes it slightly less useful in a smoothie, but infinitely better when it’s hot and you’ve been sweating like crazy (especially if you throw some ice in your shaker).
Future Whey is equally useful for hardcore bodybuilders after completing a super set, HIIT based athletes smashing out some hard paced aerobic activity or endurance athletes who are under the scorching sun all day long.
We expect many people will use Future Whey as an additional protein source – alongside whey or a vegetable based protein.
Functionally, it’s a rapidly absorbing protein so it’s an excellent choice around training time (pre, intra or post). Given the rapid absorption time, it would not be the best choice directly before bed when a slower absorbing, or even higher fat protein source is ideal.
We see a very exciting use for Future Whey by those dieting and doing competition preparation, as it’s here where many people eliminate whey. Anyone who has issues with dairy and finds stomach discomfort a problem will likely love Future Whey too.
I’m convinced, how do I get my hands on Future Whey?
Future Whey Development References
At Bulk Nutrients, we’re always all for transparency. Future Whey was formulated based on a combination of the following literature:
- Amirsasan, R., Nikookheslat, S., Sari-Sarraf, V., Kaveh, B. and Letafatkar, A. (2011) The effects of two differenct dosages of BCAA supplementation on a serum indicators of muscle damage in wrestlers. International Journal of Wrestling Science, 1(2), 32-36.
- Atherton, P.J., Etheridge, T., Watt, P.W., Wilkinson, D., Selby, A., Rankin, D., Smith, K., Rennie, M.J. (2010) Muscle full effect after oral protein: Time-dependent concordance and discordance between human muscle protein synthesis and mtorc1 signaling. American Journal of Clinical Nutrition, 92(5), 1080-1088.
- Atherton, P.J., Kumar, V., Selby, A.L., Rankin, D., Hildebrandt, W., Phillips, B.E., Williams, J.P., Hiscock, N. and Smith, K. (2016) Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men. Clinical Nutrition, in press, 1-8.
- Bahri, S., Zerrouk, N., Aussel, C., Moinard, C., Crenn, P., Curis, E., Chaumeil, J.C., Cynober, L. and Sfar, S. (2013) Citrulline: from metabolism to therapeutic use. Nutrition, 29(3), 479-484.
- Brodnik, Z., Bongiovanni, R., Double, M. and Jaskiw, G.E. (2012) Increased tyrosine availability increases brain regional DOPA levels in vivo. Neurochemistry International, 61, 1001-1006.
- Brosnan, J.T. and Brosnan, M.E. (2010) Creatine metabolism and the urea cycle. Molecular genetics and Metabolism, 100, S49-52.
- Bukhari, S.S., Phillips, B.E., Wilkinson, D.J., Limb, M.C., Rankin, D., Mitchell, W.K., Kobayashi, H., Greenhaff, P.L., Smith, K. and Atherton, P.J. (2015). Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women, at rest and after exercise. American Journal of Physiology, Endocrinology and Metabolism, 308(12), E1056-1065.
- Castell, L.M., Poortmans, J.R., Leclercq, R., Brasseur, M., Duchateau, J. and Newsholme, E.A. (1997) Some aspects of the acute phase response after a marathon race, and the effects of glutamine supplementation. European Journal of Applied Physiology and Occupational Physiology, 75, 47-53.
- Churchward-Venne, T.A., Burd, N.A., Mitchell, C.J., West, D.W.D., Philp, A., Marcotte, G.R., Baker, S.K., Baar, K., Phillips, S.M. (2012) Supplementation of a suboptimal protein dose with leucine or essential amino acids: Effects on myofibrillar protein synthesis at rest and following resistance exercise in men. The Journal of Physiology, 590(11), 2751-2765.
- Cruzat, V.F., Krause, M and Newsholme, P. (2014) Amino acid supplementation and impact on immune function in the context of exercise. Journal of the International Society of Sports Nutrition, 11, 61.
- Cruzat, V.F., Pantaleao, L.C., Donato, H., de Bittencourt, P.I. and Tirapegui, J. (2014) Oral supplementations with free and dipeptide forms of L-glutamine in endotoxermic mice: effects on muscle glutamine-glutathione axis and heat shock proteins. Journal of Nutrition and Biochemistry, 25, 345-352.
- Cruzat, V.F., Tirapegui, J. (2009) Effects of oral supplementation with glutamine and alanyl-glutamine on glutamine, glutamate and glutathione staus in trained rats and subjected to long-duration exercise.
- Cury-Boaventura, M.F., Levada-Pires, A.C., Folador, A., Gorjao, R., Alba-Loureiro, T.C., Hirabara, S.M., Peres, F.P., Silva, P.R., Curi, R. and Pithon-Curi, T.C. (2008) Effects of exercise on leukocyte death; prevention by hydrolysed whey protein enriched with glutamine dipeptide. European Journal of Applied Physiology, 103, 289-294.
- Da Luz, C.R., Nicastro, H., Zanchi, N.E., Chaves, D.F.S. and Lancha, A. H. (2011) Potential therapeutic effects of branched chain amino acids supplementation on resistance exercise-based muscle damage in humans. Journal of the International Society of Sports Nutrition, 8, 23.
- Deijen, B. (2005) Tyrosine. In: Lieberman, H.R., Kanarek, R.B., Orbleke, J.F. (Eds). Nutrition Brain and Behaviour. CRC Press, Boca Raton, 363-381.
- Dickinson, J.M., Gundermann, D.M., Walker, D.K., Reidy, P.T., Borack, M.S., Drummond, M.J., Arora, M., Volpi, E., Rasmussen, B.B. (2014) Leucine enriched amino acid ingestion after resistance exercise prolongs myofribillar protein synthesis and amino acid transporter expression in older men. Journal of Nutrition, 144(11), 1694-1702.
- Dorrell, H. and Gee, T. (2015) The acute effects different quantities of branched chain amino acids have on recovery of muscle function. UK Strength and Conditioning Annual Conference 2015, 1-2 August, Chesfold Grange, Warwickshire.
- Dreyer, H.C., Drummond, M.J., Pennings, B., Fujita, S., Glynn, E.L., Chinkes, D.L., Dhanani, S., Volpi, E. and Rasmussen, B.B. (2008) Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle. American Journal of Physiology, Endocrinology and Metabolism, 294(2), E392-400.
- English, K.L., Mettler, J.A., Ellsion, J.B., Arentson-Lontz, E., Pattarini, J.M., Ploutz-Snyder, R., SheffieldMoore, M., Paddon-Jones, D. (2016) Leucine partially protects muscle madd and function during bed resin in middle aged adults. American Journal of Clinical Nutrition, 103(2), 465-473.
- Gee, T.I. and Deniel, S. (2016) Branched chain amino acid supplementation attenuates a decrease in power producing ability following acute strength training. The Journal of Sports Medicine and Physical Fitness, Epublished Jan 20, 2016.
- Gleeson, M. (2008) Dosing and efficacy of glutamine supplementation in human exercise and sport training. The Journal of Nutrition, 138, 2045-2049S.
- Gleeson, M., Nieman, D.C. and Pedersen, B.K. (2004) Exercise, nutrition and immune function. Journal of Sports Sciences, 22, 115-125.
- Glynn, E.L., Fry, C.S., Timmerman, K.L., Drummond, M.J., Volpi, E., Rasmussen, B.B. (2013) Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism. Journal of Nutrition, 143(3), 307-314.
- Ham, D.J., Caldow, M.K., Lynch, G.s. and Koopman, R. (2014) Lecuine as a treatment for muscle wasting: a critical review. Clinical Nutrition, 33(6), 937-945.
- Hiscock, N. and Pedersen, B.K. (2002) Exercise induced immunodeprssion – plasma glutamine is not the link. The Journal of Applied Physiology, 93, 813-822.
- Hiscock, N., Petersen, E.W., Kryzkowski, K., Boza, J., Halkjaer-Kristensen, J. and Pedersen, B.K. (2003) Glutamine supplementation further enhances exercise induced plasma IL-6. The Journal of Applied Physiology, 95, 145-148.
- Howatson, G., Hoad, M., Goodall, S., Tallent, J., Bell, P.G., French, D.N. (2012) Exercise induced muscle damage is reduced in resistance trained males by branched chain amino acids: a randomised, double blind, placebo controlled study. Journal of the International Society of Sports Nutrition, 9, 20.
- Jackman, S.R., Witard, O.C., Jeukendrup, A.E. and Tipton, K.D. (2010) Branched chain amino acid ingestion can ameliorate soreness from eccentric exercise. Medicine & Science in Sports & Exercise, 42(5), 962-970.
- Jafari, H., Ross, J.B. and Emhoff, C.W. (2016) Effects of branched chain amino acid supplementation on exercise performance and recovery in highly endurance trained athletes. The FASEB Journal, 30(1), 683.
- Jongkees, B.J., Hommel, B., Kuhn, S. and Colzato, L.S. (2015) Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands – A review. Journal of Physchiatric Research, 70, 50-57.
- Katsanos, C.S., Kobayashi, H., Sheffield-Moore, M., Aarsland, A., Wolfe, R.R. (2006) A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. American Journal of Physiology, Endocrinology and Metabolism, 291, E381–387.
- Kimball, S.R. and Jefferson, L. S. (2006) Signaling pathways and molecular mechanisms theough which branched chain amino acide mediate translational control of protein synthesis. The Journal of Nutrition, 136(1), 227-231S.
- Koopman, R., Verdijk, L., Manders, R.J., Gijsen, A.P., Gorselink, M., Pijpers, E., Wagenmakers, A.J., van Loon, L.J. (2006) Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men. American Journal of Clinical Nutrition, 84, 623–632.
- Koopman, R., Verdijk, L.B., Beelen, M., Gorselink, M., Kruseman, A.N., Wagenmakers, A.J., Kuipers, H., van Loon, L.J. (2008) Co-ingestion of leucine with protein does not further augment post-exercise muscle protein synthesis rates in elderly men. British Journal of Nutrition, 99, 571– 580.
- Koopman, R., Wagenmakers, A.J., Manders, R.J., Zorenc, A.H., Senden, J.M., Gorselink, M., Keizer, H.A., van Loon, L.J. (2005) Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects. American Journal of Physiology, 288(4), E645-53. 20.
- Kryzwkowski, K., Petersen, K.W., Ostrowski, K., Kristensen, J.H., Boza, J. and Pedersen, B.K. (2001) Effect of glutamine supplementation on exercise induced changes in lymphocyte function. American Journal of Physiology – Cell Physiology, 281, 1259-1265.
- Kuhn, K.P., Harris, P.A., Cunningham, G.R., Robbins, I.M., Summar, M.L. and Christman, B.W. (2006) Oral citrulline elevates plasma arginine levels for 24 hours in normal volunteers. Circulation AHA Scientific Sessions, Abstract 1692, 1339.
- Luiking, Y.C., Abrahamse, E., Ludwig, T., Boirie, Y., Verlaan, S. (2016) Protein type and caloric density of protein supplements modulate postprandial amino acid profile through changes in gastrointestinal behaviour: A randomized trial. Clinical Nutrition, 35, 48-58.
- Matsummoto, K., Koba, T., Hamada, K., Sakurai, M., Higuchi, T. and Miyata, H. (2009) Branched chain amino acid supplementation attenuates muscle sorenss, muscle damage and inflammation during an intensive training program. The Journal of Sports Medicine and Physical Fitness, 49, 424-431.
- Miller, S.L., Tipton, K.D., Chinkes, D.L., Wolf, S.E., Wolfe, R.R. (2003) Independent and combined effects of amino acids and glucose after resistance exercise. Medicine & Science in Sports & Exercise, 35, 449–455.
- Mitchell, W.K., Phillips, B.E., Williams, J.P., Rankin, D., Lund, J.N., Wilkinson, D.J., Smith, K., Atherton, P.J. (2015) The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: clinical efficacy of pulse vs bolus supply. American Journal of Physiology, Endocrinology and Metabolism, 309(5), E450-457.
- Mitchell, W.K., Phillips, B.E., Williams, J.P., Rankin, D., Lund, J.N., Smith, K. and Atherton, P.J. (2015) A dose rather than delivery profile-dependent mechanism regulates the “muscle full” effect in response to oral essential amino acid intake in young men. The Journal of Nutrition, 145(2), 207-214.
- Moberg, M., Apro, W., Ekblom, B, van Hall, G., Holmberg, H.C. and Blomstrand, E. (2016) Activation of mTORC1 by leucine is potentiated by branched chain amino acids and even more so by essential amino acids following resistance exercise. American Journal of Physiology, 310(11), C874-884.
- Moinard, C., Nicolis, I., Neveux, N., Darquy, S., Benazeth, S. and Cynober, L. Dose ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the citrudose pharmacokinetic study. British Journal of Nutrition, 99, 855-862.
- Newsholme, P. (2001) Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection? The Journal of Nutrition, 131, 2515-2522S.
- Nosaka, K., Sacco, P. and Mawatari, K. (2006) Effects of amino acid supplementation on muscle soreness and damage. International Journal of Sport Nutrition and Exercise Metabolism, 16(6), 620635.
- Osowska, O., Moinard, C. ,Neveux, N. and Cynober, L. (Citrulline increase arginine pools and restores nitrogen balance after massive intestinal resection. Gut, 53(12), 1781-1786.
- Rieu, I., Balage, M., Sornet, C., Giraudet, C., Pujos, E., Grizard, J., Mosoni, L., Dardevet, D. (2006) Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia. The Journal of Physiology, 575, 305–315.
- Roth, E. (2008) Nonnutritive effects of glutamine. The Journal of Nutrition, 138, 2025-2031S.
- Schweldhelm, E., Maas, R., Freese, R., Jung, D., Lukacs, Z., Jambrecina, A., Spickler, W., Schulze, F. and Boger, R.H. (2007) Pharmacokinetic and pharmacodynamics properties of oral L-citrulline and Larginine: impact on nitric oxide metabolism. British Journal of Clinical Pharmacology, 65, 51-59.
- Sharp, C.P. and Pearson, D.R. (2010) Amino acid supplements and recovery from high intensity resistance training. Journal of Strength and Conditioning Research, 24(4), 1125-1130.
- Shimomura, Y. and Harris, R.A. (2006) Metabolism and physiological function of branched chain amino acids: discussion of session 1. The Journal of Nutrition, 136(1). 232-233S
- Shimomura, Y., Kobayashi, H., Mawatari, K., Akita, K., Inaguma, A., Watanabe, S., Bajotto, G., Sato, J. (2009) Effects of squat exercise and branched-chain amino acid supplementation on plasma free amino acid concentrations in young women. Journal of Nutritional Science and Vitaminology (Tokyo), 55(3), 288-291.
- Tipton, K.D., Elliott, T.A., Ferrando, A.A., Aarsland, A.A, Wolfe, R.R. (2009) Stimulation of muscle anabolism by resistance exercise and ingestion of leucine plus protein. Applied Physiology, Nutrition and Metabolism, 342, 151-61.
- Tipton, K.D., Ferrando, A.A., Phillips, S.M., Doyle, D. Jr., Wolfe, R.R. (1999) Postexercise net protein synthesis in human muscle from orally administered amino acids. American Journal of Physiology, 276(4), E628-E34.
- Tipton, K.D., Gurkin, B.E., Matin, S., Wolfe, R.R. (1999) Nonessential amino acids are not necessary to stimulate net muscle protein synthesis in healthy volunteers. The Journal of Nutritional Biochemistry, 10, 89–95.
- Usher-Smith, J.A., Huang, C.L.H. and Fraser, J.A. (2009) Control of cell volume in skeletal muscle. Biological Reviews of the Cambridge Philosophical Society, 84, 143-159.
- Volpi, E., Kobayashi, H., Sheffield-Moore, M., Mittendorfer, B., Wolfe, R.R. (2003) Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. American Journal of Clinical Nutrition, 78, 250–258.
- Wagenmakers, A.J. (1999) Tracers to investigate protein and amino acid metabolism in human subjects. Proceedings of the Nutrition Society, 58, 987–1000.
- Wernerman, J. (2008) Clinical use of glutamine supplementation. The Journal of Nutrition, 138, 20402044S.
- Wilkinson, D.J., Hossain, T., Hill, D.S., Phillips, B.E., Crossland, H., Williams, J., Loughna, P., Churchward-Venne, T.A., Breen, L., Phillips, S.M., Etheridge, T., Rathmacher, J.T., Smith, K., Szewczyk, N.J. and Atherton, P.J. (2013) Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism. The Journal of Physiology, 591(11), 2911–2923.
- Witard, O.C., Jackman, S.R., Breen, L., Smith, K., Selby, A., Tipton, K.D. (2014) Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise. American Journal of Clinical Nutrition, 991, 86-95.
- World Health Organisation, Food and Agriculture Organization of the United Nations, United Nations University (2007) Protein and amino acid requirements in human nutrition: Report of a Joint FAO/WHO/UNU expert consultation (WHO technical report series 935). 135-152. ISBN: 92 4 120935 6.
- Wyss, M. and Kaddurah-Dauok, A. (2000) Creatine and creatinine metabolism. Physical Review Letters, 80, 1107-1213.
- Young, V.R., Borgonha, S. (2000) Nitrogen and amino acid requirements: the Massachusetts Institute of Technology amino acid requirement pattern. J Nutr 130:1841S–1849S, 2000.
- Zuhl, M.N, Dokladny, K., Mermier, C., Schneider, S., Salgado, R. and Mosely, P. (2015) The effects of acute oral glutamine supplementation on exercise induced gastrointestinal permeability and heat shock protein expression in peripheral blood mononuclear cells. Cell Stress and Chaperones, 20(1), 85-93.
- Zuhl, M.N., Lanphere, K.R., Kravitz, L., Mermier, C.M., Schneider, S., Dokladny, K. and Moseley, P.L. (2014) Effects of oral glutamine supplementation on exercise induced gastrointestinal permeability and tight junction protein expression. Journal of Applied Physiology, 116, 183-191.